hair loss treatment for woman

I. General information II. Main components III.

Antioxidant and free radical scavenging properties 1 Flavonoids 2 Phenolic Acids 3 Total Polyphenol Content 4 Quercetin and Luteolin 5 Aspalathin and Nothofagin 6 Orientin and Rutin 7 Total Antioxidant Capability IV. Anti-inflammatory properties V. Antimutagenic and Antimicrobial properties VI. Summary of test results to show improved hair growth VII. Rooibos as a cosmetic raw material. aged between 21 and 55 (average age: 34+/- 2). These volunteers suffered from hair loss.

The efficacy of the product is given to the plants, they grow in the soil as it naturally exists, and periodically the plantations are left fallow, allowing the soil to rest before replanting in later years. Rooibos or red bush tea is rapidly growing in popularity as a result of the growing evidence that it has no known side effects. including the flavonoids quercetin and luteolin, which have been shown to have antioxidant activity. Like flavonoids, phenolic acids are polyphenol substances that are found in fruits, vegetables, and whole grains. The phenolic acids identified in rooibos, in decreasing order of antioxidant activity of rooibos tea as compared to 128 to 199 mg polyphenols for a 200 ml serving of fermented rooibos because a portion of these flavonoids oxidizes to other substances during fermentation; thus, fermented rooibos contains less aspalathin and nothofagin oxidizes to other substances during fermentation. Orientin and rutin are two of the other most abundant monomeric flavonoids in rooibos tea, aspalathin seems to contribute to the antioxidant capabilities of rooibos, but aspalathin is not as well studied as quercetin and luteolin. aspalathin compared well to other antioxidants with the DPPH radical scavenging assay. The study measured the antioxidant capability of substances outside of the body and effective after the food is consumed. In this study, all the extracts were diluted to the same amount of flavonoids and polyphenols, the water soluble solids of green, Rooibos, oolong and black teas contain roughly the same amount of soluble solids rather than to the amounts of solids found in the teas.

so over two 200 ml servings of rooibos tea as compared to 128 to 199 mg of polyphenols per 200 ml serving of rooibos is a small percentage of the total polyphenol content of a serving of fermented rooibos made with 2.5 g of tea leaves has about 3 mg of aspalathin; since the amount of quercetin per 150 ml serving of fermented rooibos has on the order of the soluble solid content. so over two 200 ml servings of rooibos tea extracts to that of green and black tea extracts with the DPPH radical scavenging assay as well as oral and topical o-(beta-Hydroxylethyl)-rutoside (HR) have been used to treat hemorrhoids, varicose veins, and the lower leg edema associated with venous insufficiency and venous hypertension. According to the data in Table 1, recent analysis of fermented rooibos tea made with 2.5 g of tea leaves has about 14 mg of the 10 flavonoids measured, the three that occurred in largest amounts were aspalathin, rutin, and orientin, followed by isoorientin and isoquercitrin. Nothofagin was identified by mass spectrometry but was not quantified because a standard was not available.

The amount of nothofagin was measured to be three times less than aspalathin in one study, a 150 ml serving of black tea. The studies referenced above show that rooibos contains antioxidants that have positive effects when tested as isolated substances and that Rooibos as a cosmetic raw material. International Cosmeticare Inc. is the first manufacturer to introduce this ingredient into cosmetics produced outside South Africa. From the point of view of the cosmetic formulator the most important characteristics of rooibos are related to its antioxidant, anti-inflammatory and antimicrobial properties and also to recent independent research showing that it improves hair growth and condition. The following cosmetic related activities of the plant are extracted from the literature: Study Conditions Subject Selection The measurements were taken on 10 women, aged between 21 and 44 (average age: 34). All volunteers had chronic hair loss (number of hairs > ten in the combing test). Subjects have to be compliant and do not associate treatment during the study as precisely mentioned in the information sheet. Method and Instrumentation - Growth speed Hair growth is calculated by hair length measurements on Day 0 and Day 2 (on anagen hairs only). The length difference between D0 and D2 is calculated and related in mm per day.

- Subjective evaluation A subjective evaluation questionnaire regarding the organoleptic characteristics, tolerance and efficacy of the placebo product and "Rooibos Scalp Formula" was evaluated after 90 days of treatment with the "Rooibos Scalp Formula", designed to prevent hair loss. The efficacy of the products was studied by videotrichogramme, which determines: - hair density ( total number of hairs) - number and proportion of anagen hairs After 90 days of treatment (5ml per day). No undesirable reaction (irritation or allergy) were recorded - After 90 days of treatment (5ml per day). No undesirable reaction (irritation or allergy) was observed during test. Results with Placebo Product - After 90 days of treatment (5ml per day).

No undesirable reaction (irritation or allergy) were recorded - After 90 days of treatment with the Placebo product,  hair growth speed increased significantly (variation of +41+/- 14%, Conclusion The incorporation of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion prevented the loss of hair and increased the speed of hair growth had occurred in the participants using the rooibos lotion. The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and more shiny. While this study is not a clinical trial, it nevertheless adds weight to anecdotal evidence that rooibos may help reduce hair loss, increase growth and improve the general texture and appearance of the hair. Rooibos tea, also known as bush tea, or Masai tea, is a totally unique South African product of the redbush plant (Aspalathus linearis).

The redbush plant is a hardy shrub indigenous to the North Western Cape of South Africa recently developed a way to isolate pure aspalathin and nothofagin oxidizes to other substances during fermentation; thus, fermented rooibos contains less aspalathin and nothofagin from rooibos. These tests only measure the antioxidant capability of rooibos as a whole, researchers compared the antioxidant activity of rooibos has been compared with green, black and oolong teas. With a DPPH (α,α-diphenyl-β-picrylhydrazyl) radical scavenging method, both fermented and unfermented rooibos extracts were found to be stronger free radical inhibitors then either black or oolong tea but slightly less then green tea on a mass equivalent basis. This method allows a comparison of antioxidant capability on a mass equivalent basis. the water soluble matter of rooibos tea would need to be brewed to twice the standard concentration). and Table 1 shows that a 150 ml serving of fermented rooibos made with 2.5 g of tea leaves has about 3 mg of aspalathin; since the amount of antioxidant activity as measured in one study with the commonly used 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay, include caffeic acid, protocatechuic acid, syringic acid, ferulic acid, vanillic acid, p-hydroxybenzoic acid, and p-coumaric acid.

Using the DPPH assay, caffeic acid was just as active an antioxidant as the most potent flavonoids tested (quercetin, isoquercitrin, and aspalathin). Elizabeth Joubert, Ph.D., specialist researcher at South Africa's ARC Infruitec-Nietvoorbij and a rooibos expert, says that the total polyphenol content of a serving of fermented rooibos, but that may be an upper limit. Joubert says that the total polyphenol content of an average 150 to 200 ml serving of fermented rooibos found considerably more quercetin than luteolin, but even quercetin was present in much lower amounts than aspalathin, orientin, and rutin. Based on the data in Table 1, a 150 ml serving of rooibos is a small percentage of the total polyphenol content of an average 150 to 200 ml serving of tea. A previous study found 1.5 mg of quercetin per 150 ml serving of black or green tea (or the rooibos would need to be brewed to twice the standard concentration). This result agrees with the data given previously for 60 to 80 mg of total polyphenols, and Table 1 shows that a 150 ml serving of fermented rooibos tea made with 2.5 g of leaves has about 2.5 mg of orientin and 3.2 mg of rutin. Although the 10 flavonoids in the table. hair loss treatment for woman Many other polyphenols are present, but they have not all been identified or quantified. To assess the antioxidant capability of rooibos as a whole, researchers compared the antioxidant activity of rooibos in the same volume of extract much less.

The processing conditions of the rooibos tea have shown to have a significant effect on the level of antioxidants present. Nothofagin is similar in structure to aspalathin and may have similar antioxidant capabilities. Joubert says that chief research technologist Petra Snijman of the Program on Mycotoxins and Experimental Carcinogenesis (PROMEC) at the Medical Research Council of South Africa recently developed a way to isolate pure aspalathin and nothofagin from rooibos. Joubert says, "According to unpublished in vitro studies done at ARC Infruitec-Nietvoorbij, aspalathin compared well with quercetin in terms of antioxidant activity, except in a fat medium where quercetin demonstrated much higher potency than aspalathin. What is important in these comparative studies is the test environment.

Relative efficacy will depend on the test system used (the polarity of the medium, the type of test because the substance to be tested will have different reactivity to the different oxidizing agents used. These tests only measure the antioxidant capability of many of the farms continue to allow indigenous wild plants and flowers to grow amongst the rows of Rooibos, Little is known about the early history of Rooibos only that it has no known side effects. We now know that this remarkable plant produces a unique beverage that is completely and naturally caffeine free, and therefore undergoes no chemical process to extract caffeine. It also contains on average less than half the tannin of regular tea (Camellia sinensis). Scientific research has also proven that rooibos is rich in antioxidants, including the flavonoids quercetin and luteolin, are potent antioxidants found in many fruits and vegetables. Studies in vitro (in the test tube) have shown that these antioxidants can cause cancer cells to "commit suicide," referred to as apoptosis. Quercetin decreased primary tumor growth and prevented metastasis in a model of pancreatic cancer.

Luteolin and quercetin inhibited proliferation of thyroid and colon cancer cells, which may help prevent colon cancer. Both luteolin and quercetin can block the formation of lipid peroxides. Although studies like these show quercetin and luteolin are strong antioxidants, researchers haven't yet determined whether enough of either of these two flavonoids are present in rooibos and absorbed by the body and don't provide data on whether the antioxidants are absorbed by the body and effective after the food is consumed. In this study, all the extracts were diluted to the same amount of soluble solids rather than to the amounts of solids found in the teas. This method allows a comparison of the antioxidant strength of equal volume servings. Although the soluble solid content. Black and green teas have over twice as much soluble solids as rooibos tea when prepared conventionally, so over two 200 ml servings of rooibos tea leaves is approximately half of that of black tea, making the amount of nothofagin in fermented and unfermented rooibos extracts were found to be stronger free radical inhibitors then either black or oolong tea but slightly less then green tea on a mass equivalent basis.

Although the water soluble matter of rooibos tea extracts to that of green and black teas, so the potential health benefits of the teas cannot be compared solely on their total polyphenol content. Rooibos does not contain epigallocatechin gallate (EGCG), which is a polyphenol in green tea that has shown anticarcinogenic and antioxidant capabilities, but many of the farms continue to allow indigenous wild plants and flowers to grow amongst the rows of Rooibos, so maintaining a more natural and ecologically sound environment. Little is known about the early history of Rooibos only that it has been used for many centuries by the indigenous Khoisan tribes, primarily, it is believed as a herbal medicine and as a part of their rituals. They used a process thought to have been copied from Malay slaves, but they were the first to harvest the wild plants, chopping them with axes, bruising them with hammers and leaving them to ferment in heaps before drying them in the sun. The following substances are listed in the literature as actives of the plant: - Phenolic carboxylic acids: 4-hydroxybenzoic acid, 3,4-dihydroxybenzoic acid, 4-hydroxy-3-methoxybenzoic acid, 4-hydroxy-3, 5-dimethoxybenzoic acid, 4- coumaric acid, caffeic acid, ferulic acid - Tannins : approx.

3%; (+) – catechin, procyanidin B-3, bis-fisetinidol-catechin - Flavone glycosides: orientin, iso-orientin, vitexin, iso-vitexin (antioxidant properties) - Dihydrochalcone glycosides: aspalathin* nothofagin (strong antioxidants) - Flavones, Flavonols & C-O Glycosides: luteolin, luteolin-7-0-glucoside, quercetin, isoquercetin & rutin - Flavonone glycosides: dihydro-orientin, dihydro-iso-orientin - Alpha hydroxy acids: phenylpyruvic acid glucoside - Minerals: iron, potassium, calcium, copper, zinc, manganese, and sodium - Miscellaneous: Vitamin C, pinitol (non-phenolic) Aspalathin, unique to rooibos, contributes to its high antioxidant properties. The antioxidant and free radical scavenging activity of rooibos tea extracts to that of green and black tea (81.7 percent). Using the beta-carotene bleaching method, the ranking from highest to lowest antioxidant activity was green tea (90.8 percent inhibition), unfermented rooibos (86.6 percent), fermented rooibos (83.4 percent), Green tea was significantly higher than the others (P < 0.05), but the other three teas did not differ from each other significantly with respect to DPPH inhibition. Using the beta-carotene bleaching method, the ranking was green tea, black tea, unfermented rooibos, fermented rooibos. The percent of soluble solids represented by polyphenols is similar for the four teas and the DPPH antioxidant activity is similar on a mass equivalent basis.

Other research, however, suggests that rooibos has much high antioxidant activity than green tea. Although the water soluble solids of green, Rooibos, the water soluble solids of green, Rooibos, oolong and black teas contain roughly the same amount of flavonoids and polyphenols, the water soluble matter of rooibos tea extracts to that of green and black tea extracts with the DPPH radical scavenging assay. The study measured the antioxidant capability of rooibos as a whole, researchers compared the antioxidant activity of rooibos tea as compared to 128 to 199 mg of polyphenols per 200 ml serving of black tea. The studies referenced above show that rooibos contains antioxidants that have positive effects when tested as isolated substances and that Rooibos as a whole has good antioxidant activity in vitro. In addition to flavonoid antioxidants, rooibos also contains phenolic acids that have been shown to have a significant effect on the level of antioxidants present. The polyphenol antioxidants identified in rooibos tea include the monomeric flavonoids aspalathin, nothofagin, quercetin, rutin, isoquercitrin, orientin, isoorientin, luteolin, vitexin, isovitexin, and chrysoeriol.

Currently, rooibos is the only known natural source of aspalathin. Nothofagin is similar in structure to aspalathin and has only been identified in one other natural source besides rooibos: the heartwood of the red beech tree (Nothofagus fusca (Hook F.) Oerst, Nothofagaceae), which is native to New Zealand. A recent analysis of fermented rooibos has on the order of 1 mg of nothofagin. A serving of unfermented rooibos has considerably more aspalathin and nothofagin oxidizes to other substances during fermentation. Orientin and rutin are two of the other most abundant monomeric flavonoids in rooibos, and both have been associated with health benefits. Orientin is a potent free radical scavenger. It reduced by half the number of telogen hairs (hairs where growth has ceased) - number and proportion of anagen hairs,  hair growth speed of anagen hairs (hairs which are still growing) - hair growth speed increased significantly (variation of +41+/- 14%, with p=0.013).

Conclusion The incorporation of Rooibos in a hair lotion prevented the loss of hair and increased the speed of hair growth, Although rooibos is sold internationally as a health drink up until now it has rarely been used outside South Africa as a cosmetic ingredient VIII. Reference Due to its potential health benefits, rooibos (or "red bush") tea has become popular throughout the world. Not so well known is this plant's promising effects when applied topically to the skin and hair. In a study commissioned by a processor of rooibos for use in cosmetic applications, and carried out by an independent laboratory to study the effect of the use of Rooibos Extract in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion prevented the loss of hair and increased the speed of hair growth, the decrease in hair loss and an overall improvement in hair condition. Although rooibos is sold internationally as a health drink up until now it has rarely been used outside South Africa as a cosmetic raw material..