Capsule filling machine with new technology
In one woman, pregnancy was terminated due to spina bifida in the fetus and she was discharged on albendazole and phenytoin. The second woman was put on carbamazepine: she had an emergency Cesarean section at term for fetal distress and delivered a healthy baby.Photoreceptor Recovery Following Laser Photocoagulation and Albendazole in Diffuse Unilateral Subacute Neuroretinitis
Interpack 2011, in Düsseldorf, Bosch Packaging Technology is presenting its GKF 2500 capsule filling machine with new technology for microdosing powdered pharmaceuticals. This new development is particularly suitable for processing highly effective inhalation products within filling ranges of 2-30 milligrams. "With this machine our customers can fill even very small quantities at high output levels," explained Product Manager Melanie Beck. The GKF 2500 now allows for the flexible, high-performance processing of an extremely wide range of products with varying requirements.
In the first part of the current study, the influence of water quantity and extrusion speed was investigated for a highly soluble drug product at a fixed concentration in the formula. A design of experiments underlined significant differences between the three extrusion systems. This article will continue to compare radial, dome, and axial single screw extruder in terms of process and pellet quality. This article specifically will investigate the influence of formulation and spheronization variables on process and pellet properties by using a response surface design of experiments, a powerful statistic tool allowing a rational study of the experimental parameters and enhanced process comprehension.
