ClusterHeadaches Africa

Oct 20, 2006 at 01:43 o\clock

Pain sufferer turns to 'shrooms'

by: JazzCH   Category: CH Articles

August 16, 2006

BY JIM RITTER Health Reporter


 

Every New Year's Eve and July 4th, Bob Wold brews a tea containing a psychedelic drug from "magic mushrooms."

Wold takes a small dose of the drug psilocybin -- just enough to make sounds more distinct and colors a bit brighter. "I get a couple giggles out of it," he said. "It's like having two or three beers."

But Wold doesn't take "shrooms" for the four-hour high. Rather, he has found that psilocybin is the only drug that prevents one of the most painful conditions known to man, cluster headaches.

 

 

 

Hundreds of cluster headache sufferers have begun to self-medicate with psilocybin and LSD. And now Harvard Medical School researchers plan to do a carefully controlled study of the drugs.

Vivid hallucinations

 

 

Wold, a 53-year-old construction contractor, began suffering cluster headaches about 25 years ago. He would get four to six headaches a day, each lasting 45 to 60 minutes. Each cluster period would last three or four months. "The pain is similar to if you hit your thumb with a hammer," he said.

Five or six years ago, Wold read an Internet posting from a man who said his cluster headaches went away after he took LSD for recreational purposes. Word spread, and other patients began taking LSD or psilocybin.

LSD can cause vivid hallucinations and distortions of color, sound, touch, etc. It also can impair judgment, leading to injury. Afterwards, users can suffer acute anxiety or depression. Psilocybin can cause vivid distortions of sights and sounds and emotional disturbances, according to the U.S. Drug Enforcement Administration.

Wold had tried about 75 legal drugs, but none worked very long. Figuring he had nothing to lose, he tried psilocybin, and found that two doses a year worked wonders. He orders spores over the Internet and grows mushrooms at his Lombard home.

"For the past five years, I've been pretty much pain-free and headache-free," he said.

Wold has formed a support group, ClusterBusters, to promote research on psychedelics. The group has heard from about 400 patients who have used psilocybin or LSD.

In a preliminary study, researchers from Harvard's McLean Hospital surveyed patients who had used psilocybin or LSD. Twenty-five of 48 psilocybin users and seven of eight LSD users reported the drugs prevented the entire cluster period when headaches normally occurred.

Studying psychedelics

 

 

"No other medication, to our knowledge, has been reported to terminate a cluster period," researchers wrote in the June 27 issue of the journal Neurology.

No one knows why psychedelics might work. But Harvard researcher Dr. John Halpern noted that the drugs share a similar structure to medications that have been approved for cluster headaches.

However, researchers acknowledged several limitations to their study, including the possibility that people with good outcomes were more likely to participate than those with poor outcomes.

Halpern and colleagues are planning a follow-up study in which a psychedelic drug would be compared to an inactive placebo.

Psilocybin and LSD are Schedule 1 drugs, meaning they are illegal unless used in research approved by the DEA and Food and Drug Administration.

Halpern warns that psilocybin and LSD "are drugs of abuse and are potentially quite dangerous. . . . My advice then is to not self-medicate but to respect our laws and to help us properly and safely conduct the research needed to find out if these substances work for real."

jritter@suntimes.com

Oct 18, 2006 at 09:48 o\clock

LSD might help cure cluster headaches

by: JazzCH   Category: CH Articles

 Link:
London, Sept15: The Beatles made a bold statement in the 60s by singing ‘Lucy in the Sky With Diamonds’, which was at that time believed to be a front for hallucinatory experiences after consuming LSD.

And now, over 40 years later, scientists have found that the taboo drug may actually have some benefits, in that they may help abort cluster headaches.

Cluster headaches is a problem which is characterized by excruciating pain that may last from fifteen minutes to up to three hours if left untreated.

In the chronic form, the attacks can happen up to eight times a day, with no period of remission lasting longer than a month.

Researchers at the Alcohol and Drug Abuse Research Center at McLean Hospital in Belmont, Massachusetts claim that their study is the first formal look at the therapeutic benefits of LSDs in 40 years.

Lead researcher Andrew Sewell says that to reduce the pain sufferers are often given supplemental oxygen, and sometimes prescribed migraine drugs, but contends these either may not work or may have the side effects.

Sewell and his colleague John Halpern interviewed 53 cluster-headache sufferers around the world, who had self-administered psychedelics in an attempt to alleviate their symptoms.

They found that use psilocybin aborted attacks in the majority (85%) of interviewees. The result of these hallucinogens was better than the use of oxygen, which stopped attacks for 52% of the patients surveyed.

The authors believe that users of LSD and psilocybin may be more likely to report good experiences than bad, as these hallucinogens are both better at preventing future attacks than conventional medicines.

"Many retrospective studies have shown strong effects that evaporated when studied properly, so we are inclined to take a sceptical stance," Nature magazine quoted Sewell, as saying.

The researchers are still not clear how the drugs might work, but are sure that they affect the brain.

LSD and psilocybin are types of amines called tryptamines, and their chemical structures are very similar to natural neurotransmitters such as serotonin.

Halpern and Sewell now want clinical trials of LSD and psilocybin to be performed to check wether this treatment works.

"We owe it to patients to determine whether this treatment works," says Sewell. "And we owe it to neurologists to provide them with accurate information so that they can effectively counsel patients."

Bureau Report