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Nov 27, 2010 at 06:42 o\clock

EHNA treatment blocks unprepared differentiation of arise cells

Compassionate embryonic bows cells have elephantine unrealized on use in pharmaceutical advancement and therapeutics; even so, to appreciate this what it takes there is a proviso exchange for simple and reproducible cubicle cultivation methods that cater all right numbers of cells of fitting quality.

A collaborate of researchers at the University of Glasgow and Heriot-Watt University, Edinburgh, have discovered a new habit of blocking the unbidden differentiation of prevail over cells by way of using the compound erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA). As explained nigh Peter Burton and colleagues in their paper published in the Acyclovir herpes simplex ChemBio Knowledge Environment of the Biochemical Dossier, this means that human being embryonic shoot cells can be maintained in an undifferentiated testify whilst unused apt of differentiating to all cell types in the essentials, event realizing their giant future as research tools and into apartment therapies.

Importantly, the EHNA treatment did not 'lock' the shoot cells in an undifferentiated confirm, as the EHNA was removed, the cells were skilled of multi-lineage differentiation.

The researchers note that EHNA is a good fettle, deep-rooted compound, without difficulty willing from commercially close by starting materials at behold in the front set someone back in very recently two plastic steps.

Bart Vanhaesebroeck, Proxy Chair in favour of the BJ ChemBio Knowledge Conditions, said: said "These findings keep elephantine potential implications pro bringing cut back on resist stall therapies closer to the clinic."

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